The Anti-Glutaminase/GLS Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GLS, and Glutaminase. This antibody recognizes Human, Mouse, Rat, and Non-Human Primate antigen. The Anti-Glutaminase/GLS Antibody has been validated for the following applications: EIA, Immunoassay, Cell Sorting, Isolation, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants